![]() ![]() An illicit Norco tablet obtained from one of the patients in this case series was analyzed, again by LC/MS, and contained 3.5 mg of fentanyl, 2.3 mg of promethazine, 39.2 mg of acetaminophen, and trace amounts of cocaine. In the 2 weeks following the March 25th health alert Vo et al reported another seven patients who had ingested illicit or “street” Norco and had presented to multiple Bay Area hospitals with “various signs and symptoms of opioid intoxication.” Serum from these 7 patients were analyzed using LC/MS and fentanyl as detected ranging from 1.6 to 10.1 ng/ml with analgesic therapeutic serum levels being reported between 0.6 to 3 ng/ml.
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